It paves the way for it to become the third Covid-19 vaccine to be authorised in the US, possibly within days.
The vaccine would be a cost-effective alternative to the Pfizer and Moderna vaccines, and can be stored in a refrigerator instead of a freezer.
he Food and Drug Administration's scientists confirme that overall the vaccine is about 66% effective at preventing moderate to severe COVID-19. The agency also said J&J's shot — one that could help speed vaccinations by requiring just one dose instead of two — is safe to use.
However, Johnson & Johnson expects to fall for short of its commitment to deliver 10 million doses of its COVID-19 vaccine by the end of February, with under 4 million to be ready to ship. The disclosure of the shortfall by Johnson & Johnson is the first public measure of exactly how far the drug company has fallen behind its production goals. Johnson & Johnson promised to deliver another 25 million by the end of March.
Results from trials conducted in the US, South Africa and Brazil found its efficacy against the worst outcomes of the virus was "similarly high" but overall protection was lower in South Africa and Brazil, where virus variants have become dominant.
Data showed it was more than 85% effective at preventing serious
illness, but only 66% effective overall when moderate cases were
included, when considering cases at least 28 days after vaccination .
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